TRC

Calum Best visits The Regenerative Clinic for Platelet Rich Plasma (PRP) therapy following rotator cuff surgery under the care of Mr. Ali Noorani. Watch Calum explain his excellent results so far.Platelet Rich Plasma (PRP) therapy is also known as Autologous Conditioned Plasma. PRP takes advantage of the blood’s natural healing properties to repair damaged cartilage, tendons, ligaments, muscle and bone. It can reduce pain, improve joint function and help you return quickly to normal activities.Mr. Ali Noorani: “Rotator cuff surgery is relatively predictable and works in about 90% of cases. However, the bigger your tear, the poorer your tendon quality and your general health means it is the less likely to heal. Therefore, quite often once surgery has fixed the mechanical problem of the tendon, we often offer patients biologics like PRP and AMPP to enhance the healing and recovery of the patient. We are finding that the use of biologics to enhance healing is making the repairs heal faster and more predictably. There is now good evidence behind this in randomised control trials to show this effect of faster healing.“To book an appointment make an enquiry or call us on 0330 2233332.

The Regenerative Clinic was able to speak with world renowned experts in the field of regenerative treatment.Clinicians from across the world have been using regenerative treatment such as Lipogems and Platelet Rich Plasma (PRP) therapy as a first line treatment for patients with great success. The Regenerative Clinic is a leader in joint preservation in the UK, treating sport injuries and joint degeneration.For more information, make an enquiry or call us at 03302233332.

Professor Wilson presents at the 5th International Joint Preservation Congress Sept 2018 in Warsaw.It is always good to share research and outcomes with colleagues from around the World. The latest Congress in Warsaw was a perfect opportunity for Professor Wilson to present data on joint preservation. He was joined on stage by Professor Carlo Tremolada discussing the merits of Lipogems for treating arthritis.Professor Wilson says:This year the focus of the meeting was pretty much on osteotomy. The interest in osteotomy is growing and growing in terms of its interest to surgeons, because it’s recognised now as the keystone to treating patients in terms of any joint preserving procedure and for alleviating the pain of arthritis.We had some great overview lectures from Ronald van Heerwarden and Kristian Kley, both part of the superb faculty.

The Polo Times, Britains largest independent Polo magazine, recently featured Human, Equine and Canine Lipogems® procedures performed in part by Professor Adrian Wilson from The Regenerative Clinic.The successful cases reflect the various benefits of regenerative medicine for both animals and humans. These incredible techniques performed by some of the UK’s best Orthopaedic, Equine and Canine Surgeons emulate how Lipogems® treatment can potentially change, and in some cases elongate, the lifespan of animals who would otherwise be rendered severely handicapped for the rest of their lives.A recent study on dogs shows the efficacy of this treatment in the animal world which. You can read more here.“Our state- of-the-art procedures are overseen by our team of leading orthopaedic surgeons and specialists. As a group we are committed to measuring outcomes and our growing patient registry shows the effectiveness of Lipogems treatment. We are pleased to change so many patients’ quality of life through this innovative treatment.” Prof. Adrian Wilson MBBS, BSc (Hons), FRCS, FRCS (Tr & Orth) The Regenerative Clinic, London, Hampshire and Windsor“Our Clinic takes a proactive approach to the use of regenerative techniques in canine patients. We have used a number of systems in recent years, none of which we have found to be as effective as Lipogems. Alistair Cliff BVM&S (Dist) CertAVP MRCVS Crown Vets Referrals, Inverness“Lipogems is a step forward for us in treating competitive sport horse injuries, whether they are tendons, ligaments or joints, because it allows us to rapidly treat them. It is a simple, straightforward and relatively non-evasive procedure that gives outstanding results.” Dr. Tim Watson BVM&S PhD MRCVS Waterlane Equine Vets, Gloucestershire

We Take Regenerative Therapy to KarachiThe Regenerative Clinic wowed Karachi with three days of education, insight and researchThe Regenerative Clinic took…

The retired American golfer Jack Nicklaus claims to have mastered his chronic back pain after receiving several experimental injections of his own stem cells.Nicklaus, 78, who won a record 18 major championships, had been afflicted with the problem since his teens, leading to surgery on his spine and nine steroid jabs. The golfer is due to have his right shoulder done next. www.thetimes.co.uk/article/nicklaus-beats-back-pain-with-stem-cell-therapy-wwqjnkj9s

Fix arthritis with LIPOSUCTION – new treatment promises to heal painful joints with injections of tummy fat Lipogems uses the natural healing cells in fat to treat arthritic knees and feet – and Mirror journalist Lynne Hyland was among the first in the UK to try it. Watch her Lipogems procedure:

In England and Wales there are approximately 160,000 total hip and knee replacement procedures performed each year, but many more struggle daily with pain and life-restricting stiffness. Revolutionary new treatments using stem cell procedures could offer a more popular alternative. Musculoskeletal pain is one of the leading causes of absence from work, and conditions like osteoarthritis can cause debilitating pain, making it difficult for sufferers to carry out normal everyday tasks. Wear and tear has caused the fibrous tissue, cartilage, to become thinned, damaged or worn away altogether, and many of these patients will eventually require a joint replacement in order to reduce pain and increase flexibility. However, there are drawbacks to surgery. The procedure usually requires 3-4 days in hospital, and a period of recuperation. Sometimes the joint will need replacement in future, however a revolutionary new treatment is set to revolutionise the way we manage joint pain. A new study released today by YouGov and The Regenerative Clinic, found that more than a third of Britons (38%) would choose the new innovative stem cell treatments over a traditional joint replacement. The figure rose to 42% in the over 55 age group.The study was conducted by YouGov with 2086 UK adults aged 18+, who were asked to imagine they needed to undergo joint replacement surgery. They were also given the option to have a non-surgical procedure called ‘Lipogems’ which takes adipose pre-cursor stem cells from your own fat and then injects them straight into your joints in order to regrow cartilage.Lipogems® is a new minimally invasive treatment that harnesses natural repair cells removed from your own body fat to target problems affecting the tendons, ligaments, joints and muscles, including osteoarthritis. Lipogems® technology has the potential to aid the repair, replacement, reconstruction and support of damaged or injured tissues without the need for joint surgery, and where surgery is required, for example, where there is very serious deterioration, it may still be of benefit in improving post-operative healing.Nearly half (45%) of Britons surveyed told researchers that stem cell procedures are the future of medicine with 48% demanding to learn more about these new emerging techniques. More men (49%) cite stem cell treatments as the future of medicine compared with 42% of women. This rises to 50% in 18 to 24 year olds.Professor Adrian Wilson of The Regenerative Clinic said;“It is an extremely exciting time for new procedures such as Lipogems. We are seeing tremendously positive results and we are encouraged by the open-mindedness of the British public who are always curious and resourceful about their health. We need to educate people about what’s available to them for both treatment and pain relief.”While the efficacy and professionalism of traditional replacement procedures within the NHS and private sector is excellent not all individuals are able to tolerate such operations. 83% of people had concerns about having joint replacement surgery with only 14% saying that they would not have any specific worries at all.Only 3% of those surveyed said that stem cell treatments like Lipogems were not for them.People in Wales were most worried about spending time in hospital, 15% compared with the national average of 9%. Recovery time worried people in Northern Ireland the most (28%) compared with the national average of 19%. Women were slightly more worried about their operation working (29%) as opposed to men (27%). Londoners and those aged 55+ were most worried about their operation working – 35% and 32% respectively.Men were most concerned with taking time off work – 10% compared with only 6% of women who were concerned with taking time off work to have a traditional joint replacement operation.For further information please visit our homepage or call the clinic on 0330 223 3332.

The orthobiologics field, which merges biological therapies with traditional orthopaedic healing and surgical techniques, is exploding. Why? Because in many circumstances, tissues can be induced to heal—or even re-grow—if the right environment is provided. Here is the latest.We have now entered the Anabolic Era of orthopaedics. In the past, surgeons would resect (cut out) torn tissues and tell patients to come back when they needed a joint replacement. Today the preferred strategy for treating (or avoiding) arthritis is to repair, regenerate, and replace injured tissues as soon as possible.Tissue engineering has been around for a long time. I was fortunate to invent one of the first commercially successful orthopedic tissue regeneration devices, called the collagen meniscus implant (CMI), in the 1980s. This collagen scaffold was designed to induce meniscus tissue to re-grow into a trellis-like material. It has now been used thousands of times worldwide.Many tissues, however, require more than just a scaffold to re-grow into; they benefit from a stimulus. Nature’s stimuli are called “growth factors”—like the testosterone hormone that children acquire in puberty to spur their growth. There are more than 1,000 different types of growth factors in human blood, and each plays a role in tissue healing. Along the walls of blood vessels live specialized cells called “stem cells.” These cells are primarily growth factor engines. They migrate to the site of an injury in the body and release their growth factors, often instructing other cells to perform specific healing activities—such as laying down new collagen fibers or forming new cartilage matrices. As you age, the number and potency of these stem cells declines.Fortunately, there are now numerous outside sources of growth factors and stem cells. Each has pros and cons in its use for stimulating tissue healing. An entire industry is growing around products to harvest and concentrate these factors for physicians’ use. There are avid proponents of each type, which come from a variety of sources. These include bone marrow (BMAC or bone marrow aspirate concentrate), fat (lipoaspirates), blood (PRP, or platelet-rich plasma), and the amnionic membrane and fluid from C-section births.My personal bias is to use amnionic sources. Why? Because there are at least 45 times more stem cells in newborns than in adults. My older patients have very few stem cells in their bone marrow, and the amount of growth factors from their own blood varies widely. I get 2 to 50 times the concentration of growth factors from amniotic sources that I would from adult blood. Fat, while very vascular, requires a separate surgical procedure that most people would prefer to avoid.I collaborate with an independent testing lab to test and confirm that each batch of the amniotic fluid I use has both live stem cells and active growth factors.Each of these techniques of anabolic stimulation has reported successful outcomes across a wide variety of musculoskeletal disorders including tennis elbow, partial tears of rotator cuffs, partial ACL tears, tendonitis, degenerative disc disease, disc herniations, bone bruises, and Achilles injuries. The clinical data is accumulating more rapidly than for any previous new therapy I have seen in the field of orthopaedics.After surgery, I use stem cells and growth factors, with their potent anabolic properties, to accelerate healing and to drive the healing of tissue toward normal regeneration rather than the formation of scar tissue. But what stem cells don’t do is turn into new cartilage. This means that they don’t actually cure arthritis, though they do mitigate the symptoms— in some patients dramatically, and for periods up to a year. The injections can be repeated without harm. In arthritic joints, stem cells release potent anti-inflammatory agents which reduce pain and may stimulate the production of more lubricating factors. These benefits seem preferable to the use of cortisone, which shuts down healing and injures tissues.Since all my patients want to heal faster and diminish their downtime, return to sports and daily activities immediately, and jump higher and fly faster, the pressure to find novel ways to harness nature and use her hidden resources to accelerate healing is huge. We aren’t sure if we can accelerate it, but it sure is worth a try.

MILAN, July 11, 2017 /PRNewswire/ — “Lipogems has been used in over 20,000 cases worldwide in a variety of clinical settings, including studies that have evaluated its use in orthopaedic pathologies. We commend the principle investigators at the Rizzoli Institute for bringing a high level scientific rigor to determine if patients with knee osteoarthritis have better functional outcomes and are more satisfied with Lipogems when compared to the biologic gold standard,” said Giorgio Ninzoli, CEO of Lipogems International. The physicians and researchers at the Rizzoli Institute are conducting the first prospective, randomized and controlled study comparing the safety and performance of a single intra-articular injection of micro-fragmented adipose tissue (Lipogems) versus platelet rich plasma (PRP) in patients with knee osteoarthritis. Click here to learn more about the study.118 patients will be randomly assigned to receive either Lipogems or PRP, which is the biologic gold standard of care for non-operative treatment of symptomatic knee osteoarthritis.The study will evaluate the improvement of the patient’s symptoms, functional recovery, and tissue architecture using Magnetic Resonance Imaging (MRI). The patients will be followed for two years post procedure.Patients enrolled in this study must have failed conservative treatment for at least three months and agree to actively participate in the rehabilitation and follow-up program.Lipogems under the microscope: Lipogems is minimally manipulated adipose tissue that maintains the cell and tissue microarchitecture. Inside of the concentrated cells, it contains important components including stem cells, pericytes, adipocytes, muse cells that are essential to help facilitate a healing microenvironment. (PRNewsfoto/Lipogems)The societal impact of degenerative diseases, such as articular cartilage pathology, is steadily increasing because patients are living longer and are more active. Patients with articular cartilage lesions may have joint pain and reduced function, and often progress to end-stage osteoarthritis, which is one of the top 10 causes of disability worldwide. Many non-invasive treatment options are available but may have limitations and may not improve patient’s mobility and quality of life. Orthopedic surgeons are seeking options to postpone surgery. Adipose tissue, commonly known as fat, has many natural reparative characteristics that help to promote a healing environment through the harmonious work of its various components, including mesenchymal stem cells (MSCs), pericytes, and other cell types embedded in its collagen scaffold. Indeed, through trophic, mitogenic, anti-scarring, anti-apoptotic, immunomodulatory, and anti-microbial actions, produced by a large amount of bioactive elements, growth factors and cytokines, these cells “sense” and “signal” changes in the microenvironment where they reside. The adipose tissue is rich in vascular niches that, besides providing a readily available source of native cushioning, could serve as a smart source of MSCs.“The use of adipose-derived MSCs, either culture-expanded or obtained by mechanical or enzymatic treatment as the stromal vascular fraction, have recently become the subject of intense interest in the field of orthopaedics and has shown some promising results,” said Carlo Tremolada, MD, plastic and cranomaxillofacial surgeon and founder of Lipogems, “However, the studies published to date used a tissue engineering approach, involving the use of scaffolds, cells, and growth factors, either alone or in some combination. In addition to requiring a large number of expensive and complex processing steps, there are significant regulatory restrictions associated with cell expansion and manipulation, and the results achieved to date are far from being completely satisfactory. Therefore, availability of a minimally manipulated adipose tissue for use in this setting would have enormous clinical relevance. The Lipogems technology overcomes all these issues. The procedure is simple, economic, quick, minimally invasive, one-step, safe and compliant.”Lipogems will provide the medical devices for the study and expenses for the patients (for example, insurance, MRI). However, physicians conducting the study will not be compensated for their effort.About Rizzoli Institute of OrthopedicsThe Rizzoli Orthopedic Institute is the main Italian institute of orthopedics and traumatology that has a status of ‘Scientific research hospital’ due to its high level of healthcare. To learn more about the Rizzoli Institute, please click here: http://www.ior.it/en/curarsi-al-rizzoli.About Lipogems CompanyLipogems is an innovative company whose vision is to bring responsible and effective reparative solutions to physicians and patients to help maintain or restore their lifestyle and improve their quality of life and recovery time. These solutions may offer an alternative for those who may not want or who are not candidates for surgery, or may be used to accelerate the healing process of those who are candidates for surgery. Additional information about Lipogems is available at www.lipogems.euSOURCE LipogemsRelated Links